Malignant peripheral nerve sheath tumor of temporoparietal region of brain mimicking as glioma: A rare case report

Malignant peripheral nerve sheath tumor (MPNST) is exceedingly rare to occur intracerebrally. The incidence of this subtype 0.001%. Their typical origin from nerves the limbs, trunk, and lumbar brachial plexuses. It carries a poor prognosis despite aggressive management due high chances local recurrence. We present case MPNST occurring intracerebrally in 60-year-old male patient. Imaging showed 63 × 74 46 mm mass lesion left temporoparietal region with effect. patient underwent craniotomy maximum gross dissection tumor. Histopathology was suggestive spindle cell neoplasm. On immunohistochemistry, cells were positive for S-100 SOX-10, which are consistent diagnosis MPNST. post-operative contrast-enhanced magnetic resonance imaging brain residual disease. Post-operative radiotherapy given intensity-modulated radiation therapy chemotherapy doxorubicin ifosfamide.